DSpace Собрание: Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating potential for societal impact.Analytical Methods welcomes early applications of new analytical and bioanalytical methods and technology demonstrating potential for societal impact.http://hdl.handle.net/20.500.12701/17552024-03-29T11:00:42Z2024-03-29T11:00:42ZIron-core/carbon-shell nanoparticles with intrinsic peroxidase activity: new platform for mimetic glucose detectionSurgutskaya, N. S.Trusova, M. E.Slepchenko, G. B.Minin, A. S.Pershina, A. G.Uimin, M. A.Yermakovc, A. E.Postnikov, P. S.http://hdl.handle.net/20.500.12701/17562022-03-30T05:13:00Z2017-03-28T00:00:00ZНазвание: Iron-core/carbon-shell nanoparticles with intrinsic peroxidase activity: new platform for mimetic glucose detection
Авторы: Surgutskaya, N. S.; Trusova, M. E.; Slepchenko, G. B.; Minin, A. S.; Pershina, A. G.; Uimin, M. A.; Yermakovc, A. E.; Postnikov, P. S.
Краткий осмотр (реферат): Artificial enzymatic mimics based on nanoparticles have become a powerful tool for the improvement of analytical performance in the detection of important bioactive compounds. For the first time the intrinsic peroxidase-like activity of Fe-core/carbon shell nanoparticles (Fe@C NPs) was studied. The catalytic process was described by a typical Michaelis–Menten curve for enzyme kinetics, and the results were comparable with those previously published. The high catalytic performance of the Fe@C NPs allows the development of a new simple procedure for glucose determination with a low detection limit of 0.21 μM. To our knowledge, this is the first study showing the ability to generate active oxygen species on the Fe@C surfaces. We suppose that our investigation will open up a new direction in medicinal applications using these promising materials.2017-03-28T00:00:00Z