DSpace Собрание: The Journal of Biomedical Optics (JBO) is an open access journal that publishes peer-reviewed papers on the use of novel optical systems and techniques for improved health care and biomedical research.The Journal of Biomedical Optics (JBO) is an open access journal that publishes peer-reviewed papers on the use of novel optical systems and techniques for improved health care and biomedical research.http://hdl.handle.net/20.500.12701/17322024-02-21T15:31:54Z2024-02-21T15:31:54ZExhaled air analysis using wideband wave number tuning range infrared laser photoacoustic spectroscopyKistenev, Yury V.Borisov, Alexey V.Kuzmin, Dmitry A.Penkova, Olga V.Kostyukova, NadezhdaKarapuzikov, Alexey A.http://hdl.handle.net/20.500.12701/17632022-03-31T03:02:56Z2017-01-25T00:00:00ZНазвание: Exhaled air analysis using wideband wave number tuning range infrared laser photoacoustic spectroscopy
Авторы: Kistenev, Yury V.; Borisov, Alexey V.; Kuzmin, Dmitry A.; Penkova, Olga V.; Kostyukova, Nadezhda; Karapuzikov, Alexey A.
Краткий осмотр (реферат): The infrared laser photoacoustic spectroscopy (LPAS) and the pattern-recognition-based approach for noninvasive express diagnostics of pulmonary diseases on the basis of absorption spectra analysis of the patient’s exhaled air are presented. The study involved lung cancer patients (
N
=
9
), patients with chronic obstructive pulmonary disease (
N
=
12
), and a control group of healthy, nonsmoking volunteers (
N
=
11
). The analysis of the measured absorption spectra was based at first on reduction of the dimension of the feature space using principal component analysis; thereafter, the dichotomous classification was carried out using the support vector machine. The gas chromatography–mass spectrometry method (GC–MS) was used as the reference. The estimated mean value of the sensitivity of exhaled air sample analysis by the LPAS in dichotomous classification was not less than 90% and specificity was not less than 69%; the analogous results of analysis by GC–MS were 68% and 60%, respectively. Also, the approach to differential diagnostics based on the set of SVM classifiers usage is presented.2017-01-25T00:00:00ZDiagnosis of oral lichen planus from analysis of saliva samples using terahertz time-domain spectroscopy and chemometricsKistenev, Yury V.Borisov, Alexey V.Titarenko, Maria A.Baydik, Olga D.Shapovalov, Alexander V.http://hdl.handle.net/20.500.12701/17332022-03-28T05:46:11Z2018-04-13T00:00:00ZНазвание: Diagnosis of oral lichen planus from analysis of saliva samples using terahertz time-domain spectroscopy and chemometrics
Авторы: Kistenev, Yury V.; Borisov, Alexey V.; Titarenko, Maria A.; Baydik, Olga D.; Shapovalov, Alexander V.
Краткий осмотр (реферат): The ability to diagnose oral lichen planus (OLP) based on saliva analysis using THz time-domain spectroscopy and chemometrics is discussed. The study involved 30 patients (2 male and 28 female) with OLP. This group consisted of two subgroups with the erosive form of OLP (n = 15) and with the reticular and papular forms of OLP (n = 15). The control group consisted of six healthy volunteers (one male and five females) without inflammation in the mucous membrane in the oral cavity and without periodontitis. Principal component analysis was used to reveal informative features in the experimental data. The one-versus-one multiclass classifier using support vector machine binary classifiers was used. The two-stage classification approach using several absorption spectra scans for an individual saliva sample provided 100% accuracy of differential classification between OLP subgroups and control group.2018-04-13T00:00:00Z