The American Journal of Tropical Medicine and Hygiene is a peer-reviewed journal published monthly by the American Society of Tropical Medicine and Hygiene and consists of two complete, sequentially numbered volumes each calendar year. http://hdl.handle.net/20.500.12701/1713 2024-02-22T14:32:37Z 2024-02-22T14:32:37Z Kovshirina, Yulia V. Fedorova, Olga S. Vtorushin, Sergey V. Kovshirina, Anna E. Ivanov, Stanislav D. Chizhikov, Andrey V. Onishchenko, Sergey V. Ogorodova, Ludmila M. Odermatt, Peter http://hdl.handle.net/20.500.12701/1714 2022-03-23T08:16:22Z 2018-12-26T00:00:00Z

Название: Case Report: Two Cases of Cholangiocarcinoma in Patients with Opisthorchis felineus Infection in Western Siberia, Russian Federation Авторы: Kovshirina, Yulia V.; Fedorova, Olga S.; Vtorushin, Sergey V.; Kovshirina, Anna E.; Ivanov, Stanislav D.; Chizhikov, Andrey V.; Onishchenko, Sergey V.; Ogorodova, Ludmila M.; Odermatt, Peter Краткий осмотр (реферат): Cholangiocarcinoma (CCA) is a cancer with high mortality owing to its aggressiveness and resistance to therapy. The liver flukes of the Opisthorchiidae family have been recognized as risk factors of CCA. Opisthorchis felineus infection occurs in Western Siberia, the biggest endemic area in the Russian Federation, and is associated with chronic inflammation of the bile ducts, which may be linked to severe hepatobiliary morbidity. We report two cases of confirmed CCA who had a chronic O. felineus infection. Both cases presented unspecific symptoms at the onset of the disease, a stage when severe pathological changes already had occurred. Both patients were living in endemic areas but did not receive any antihelminthic treatment. This report underlines the need for assessment of O. felineus infection as a causative factor of CCA. The results will provide further arguments for control of O. felineus in the Russian Federation.

2018-12-26T00:00:00Z